Ecosprin Plus 75/75mg Tablet 10pcs

✔️ Uses of Ecosprin Plus

• Prevention of heart attack and stroke

✔️ How does Ecosprin Plus work?

Ecosprin Plus reduces the risk of heart problems, whereas clopidogrel acts by irreversibly inhibiting platelet aggregation in the coronary arteries, and aspirin acts by blocking an enzyme called cyclo-oxygenase 1 which is believed to be responsible for catalyzing the synthesis of platelets, thus leading to the prevention of fatal cardiac outcomes.

✔️ Side Effects of Ecosprin Plus

• Diarrhea
• Itching
• Dizziness
• Nausea or vomiting
• Muscle pain
• Heartburn
• Change in taste
• Nosebleeds or bleeding of gums
• Bruising
• Blood in the urine or stools

✔️ Quick Suggestions:

• Take Ecosprin Plus as prescribed by your doctor.
• Administer it with or after a meal.
• Take the medicine at the same time every day for ease of remembering and better compliance.
• Do not break, chew, or crush the capsule in your mouth.
• Swallow it whole with plenty of water.
• Adhere to all the instructions provided on the prescription label or packing insert.
• Do not take Ecosprin Plus in quantities larger or smaller than prescribed.
• Report any unusual symptoms to your doctor promptly.
• Ensure that the entire treatment course is completed.
• Do not stop using this medicine without consulting your doctor.
• Your doctor may change your dose based on your clinical condition.
• Regular monitoring of hemoglobin levels may be recommended to detect any internal hemorrhages.
• Ecosprin Plus may increase the risk of bruising or bleeding.
• Avoid cutting or injuring yourself.

✔️ Indications:

Clopidogrel + Aspirin (Ecosprin Plus) is indicated for the prevention of ischemic events, myocardial infarction, stroke, and cardiovascular death in patients with acute coronary syndrome.

✔️ Pharmacology

• Ecosprin Plus is a fixed-dose combination containing Aspirin and Clopidogrel.
• Aspirin acts as an antiplatelet agent.
• It causes irreversible inhibition of the cyclo-oxygenase enzyme.
• This leads to decreased formation of Thromboxane A2.
• The action is permanent, lasting for the life of platelets (7-10 days).
• Clopidogrel selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet receptor.
• It inhibits the subsequent ADP-mediated activation of the GP llb/llla complex.
• This inhibits platelet aggregation.
• The combination is often used for its antiplatelet effects.
• It is prescribed in conditions where preventing blood clot formation is crucial.
• The dosage and administration are typically determined by healthcare professionals based on the patient's condition.
• Aspirin's effect is permanent for the life of platelets.
• Clopidogrel's effect lasts until new platelets without the drug are produced.
• The combination of Aspirin and Clopidogrel is significant in preventing platelet aggregation and blood clot formation.

✔️ Dosage & Administration of Ecosprin Plus

The recommended oral dose is one tablet daily.

✔️ Interaction

Alcohol Interaction:

• Description: N/A
• Instructions: Avoid or limit alcohol intake to prevent liver damage and reduce the risk of gastrointestinal bleeding.

Medicine Interactions:

• Corticosteroids
• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Antacids
• Amitriptyline
• SSRIs (Selective Serotonin Reuptake Inhibitors)
• Oral Anticoagulants

Disease Interactions:

Gastrointestinal Toxicity:

• Symptoms: Nausea, vomiting, diarrhea, stomach pain, etc.
• Risk: Increased risk of gastrointestinal bleeding and discomfort.
• Precaution: Use Clopitab-A 75 Capsule only under your doctor's prescription.

Gout:

• Caution: Use with care if you have gout, as it may worsen the condition.
• Action: Your doctor may recommend dose adjustments or an alternative.

Glucose-6-phosphate Dehydrogenase Deficiency:

• Caution: Use with care if you have G6PD deficiency, as it may increase the risk of hemolysis.
• Action: Your doctor may suggest appropriate adjustments or an alternative.

Food Interactions:

• Information not available.

Lab Interactions:

• Information not available.

✔️ Contraindications

Ecosprin Plus is contraindicated for conditions like Kidney Cancer, Kidney Disease, and Liver Disease.

✔️ Pregnancy & Lactation

Pregnancy: Adverse effects are increased in the mother and the fetus following chronic ingestion of Aspirin. Because of possible adverse effects on the neonate and the potential for increased maternal blood loss, this drug should be avoided during the last three months of pregnancy.

Nursing Mother: As Aspirin is excreted in breast milk, this drug should be avoided in nursing mothers because of the possible risk of developing Reye's syndrome.

✔️ Precautions & Warnings

• It should not be given to children, particularly those under 12 years. Aspirin may be a contributory factor in the causation of Reye's syndrome in some children.
• Salicylates should be used with caution in patients with a history of peptic ulceration or hemophilia and other bleeding disorders. These may also induce gastrointestinal hemorrhage.
• If a patient is to undergo elective surgery and an antiplatelet effect is not desired, Clopidogrel should be discontinued 7 days before surgery.
• It prolongs the bleeding time. So it should be used with caution in patients who may be at risk of increased bleeding from trauma, surgery, or other pathological conditions (particularly gastrointestinal and intraocular).
• Patients should be informed that it may take them longer than usual to stop bleeding when they take this drug and they should report any unusual bleeding to the physicians.
• This drug should be used with caution in hepatically and renally impaired patients.

✔️ Storage Conditions

• Keep the medicine away from the reach of children and pets.
• Dispose of unused or expired medicine properly.